- Out of all the male DS kids- Arnold, Willis, Sam, Dudley, Robbie, Charlie only 1 is NOT married- Gary Coleman
- The ONLY castmember to appear in all 189 episodes of DS was Conrad Bain
- DS had one spinoff show "Facts Of Life" and one crossover show "Hello Larry."
- DS's spinoff Facts Of Life ran one year longer than Diff'rent Strokes did.
- DS moved to ABC for its final season after it was dropped by NBC.
- Guest stars on the show included Muhammed Ali, Nancy Regan, Mr T, David Hasslehoff, Molly Ringwald.
- The creators of Silver Spoons (Howard Leeds, Ben Starr, Martin Cohan) met as producers on Diff'rent Strokes as did the
creators of Who's The Boss (Blake Hunter, Martin Cohan)